A slow RNA polymerase II affects alternative splicing in vivo

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Changes in promoter structure and occupation have been shown to modify the splicing pattern of several genes, evidencing a coupling between transcription and alternative splicing. It has been proposed that the promoter effect involves modulation of RNA pol II elongation rates. The C4 point mutation...

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Detalles Bibliográficos
Autores principales: De La Mata, M., Alonso, C.R., Kadener, S., Fededa, J.P., Blaustein, M., Pelisch, F., Cramer, P., Bentley, D., Kornblihtt, A.R.
Formato: JOUR
Materias:
elongation factor
fibronectin
protein subunit
RNA
RNA polymerase II
Adenovirus
article
cell culture
Drosophila
embryo cell
exon
gene
genetic transcription
genetic transfection
Hox gene
human
in vivo study
point mutation
protein expression
reverse transcription polymerase chain reaction
RNA splicing
RNA translation
Western blotting
Adenoviridae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10972765_v12_n2_p525_DeLaMata
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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