Porphyria-induced hepatic porphyrinogen carboxy-lyase inhibitor and its interaction with the active site(s) of the enzyme

Porphyrinogen carboxy-lyase is an enzyme that sequentially decarboxylates uroporphyrinogen III (8-COOH) to yield coproporphyrinogen III (4-COOH). In mammals this enzyme activity is impaired by hexachlorobenzene treatment, through generation of an enzyme inhibitor. The interaction of porphyrinogen ca...

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Detalles Bibliográficos
Autores principales: De Catabbi, S.B., De Calmanovici, R.W., Minutolo, C., Aldonatti, C., De Viale, L.C.S.M.
Formato: JOUR
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rat
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_10399712_v47_n6_p945_DeCatabbi
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