Paradoxical effects of tumour necrosis factor-α on rat granulosa cell DNA synthesis

Tumour necrosis factor-α (TNF-α) has been proposed as an intraovarian modulator of granulosa cell function. The effect of TNF-α on DNA synthesis in cultured rat granulosa cells was examined. Tumour necrosis factor-α stimulated thymidine incorporation when added in the presence of transforming growth...

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Detalles Bibliográficos
Autores principales:	Lanuza, G.M., Saragüeta, P.E., Bussmann, U.A., Barañao, J.L.
Formato:	JOUR
Materias:	activin A bucladesine cell DNA ceramide cyclic AMP cytokine follitropin gonadotropin sphingomyelin phosphodiesterase thymidine transforming growth factor beta tumor necrosis factor alpha activin DNA inhibin amino acid metabolism animal cell article cell culture cell differentiation cell function cell growth cell membrane permeability cell viability controlled study DNA synthesis enzyme activation female granulosa cell growth regulation hormonal regulation inhibition kinetics mitogenesis molecular mimicry nonhuman ovary follicle development ovary function paracrine signaling rat animal biosynthesis cell division comparative study cytology drug effect drug interaction metabolism Sprague Dawley rat Animalia Activins Animals Cell Division Cells, Cultured Ceramides Cyclic AMP Drug Interactions Female Follicle Stimulating Hormone Granulosa Cells Inhibin-beta Subunits Rats Rats, Sprague-Dawley Tumor Necrosis Factor-alpha
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_10313613_v14_n3-4_p133_Lanuza
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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