Participation of epididymal cysteine-rich secretory proteins in sperm-egg fusion and their potential use for male fertility regulation

Rat protein DE is an androgen-dependent cysteine-rich secretory protein (CRISP) synthesized by proximal epididymal regions. DE, also known as CRISP-1, is localized on the equatorial segment of acrosome-reacted spermatozoa and participates in gamete fusion through binding to egg complementary sites....

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Cohen, D.J., Da Ros, V.G., Busso, D., Ellerman, D.A., Maldera, J.A., Goldweic, N., Cuasnicú, P.S.
Formato: JOUR
Materias:
Contraception
Cysteine-rich secretory protein
Epididymis
Gamete fusion
Sperm
amino acid
androgen
cell protein
contraceptive agent
cysteine
egg protein
epididymal secretory protein
synthetic peptide
acrosome reaction
amino acid sequence
amino acid substitution
cell fusion
drug targeting
egg
epididymis
fertilization
gamete
genetic conservation
lizard
male fertility
molecular mechanics
nonhuman
protein binding
protein localization
protein motif
protein synthesis
regulatory mechanism
review
saliva
sequence homology
spermatozoon
Animals
Cell Fusion
Female
Germ Cells
Glycoproteins
Humans
Male
Membrane Glycoproteins
Ovum
Rats
Sperm Capacitation
Sperm-Ovum Interactions
Spermatozoa
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_1008682X_v9_n4_p528_Cohen
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares