Enhancer turnover and conserved regulatory function in vertebrate evolution

Mutations in regulatory regions including enhancers are an important source of variation and innovation during evolution. Enhancers can evolve by changes in the sequence, arrangement and repertoire of transcription factor binding sites, but whole enhancers can also be lost or gained in certain linea...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Domené, S., Bumaschny, V.F., de Souza, F.S.J., Franchini, L.F., Nasif, S., Low, M.J., Rubinstein, M.
Formato: JOUR
Materias:
Comparative genomics
Hypothalamus
Mammals
Proopiomelanocortin
Teleosts
Transgenic zebrafish
cyprinid
evolutionary biology
gene expression
hormone
mammal
mutation
neurology
turnover
POMC protein, zebrafish
proopiomelanocortin
zebrafish protein
animal
article
biology
comparative genomics
enhancer region
gene expression regulation
genetics
hypothalamus
immunohistochemistry
in situ hybridization
metabolism
molecular evolution
nerve cell
nucleotide sequence
teleost
transgenic animal
transgenic zebrafish
vertebrate
zebra fish
mammals
teleosts
Animals
Animals, Genetically Modified
Computational Biology
Conserved Sequence
Enhancer Elements, Genetic
Evolution, Molecular
Gene Expression Regulation
Immunohistochemistry
In Situ Hybridization
Mutation
Neurons
Pro-Opiomelanocortin
Vertebrates
Zebrafish
Zebrafish Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09628436_v368_n1632_p_Domene
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares