Glucocorticoid receptors and actions in the spinal cord of the Wobbler mouse a model for neurodegenerative diseases

We have studied glucocorticoid receptors (GR) and actions in the spinal cord of the Wobbler mouse, a model for amyotrophic lateral sclerosis and infantile spinal muscular atrophy. Basal and stress levels of circulating corticosterone (CORT) were increased in Wobbler mice. Single point binding assays...

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Detalles Bibliográficos
Autores principales: González Deniselle, M.C., González, S., Piroli, G., Ferrini, M., Lima, A.E., De Nicola, A.F.
Formato: JOUR
Materias:
corticosterone
dexamethasone
glial fibrillary acidic protein
glucocorticoid receptor
ornithine decarboxylase
amyotrophic lateral sclerosis
animal experiment
article
controlled study
degenerative disease
female
hereditary spinal muscular atrophy
hippocampus
male
mouse
nonhuman
receptor down regulation
spinal cord
Amyotrophic Lateral Sclerosis
Animals
Astrocytes
Cell Division
Corticosterone
Dexamethasone
Disease Models, Animal
Female
Glial Fibrillary Acidic Protein
Glucocorticoids
Lumbosacral Region
Male
Mice
Mice, Mutant Strains
Neck
Ornithine Decarboxylase
Receptors, Glucocorticoid
Sex Factors
Spinal Cord
Spinal Muscular Atrophies of Childhood
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09600760_v60_n3-4_p205_GonzalezDeniselle
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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