Local VEGF inhibition prevents ovarian alterations associated with ovarian hyperstimulation syndrome

The relationship between human chorionic gonadotropin and ovarian hyperstimulation syndrome (OHSS) is partially mediated by vascular endothelial growth factor A (VEGF). The aim of this study was to investigate the effects of VEGF inhibition on the development of corpora lutea (CL) and cystic structu...

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Autores principales:	Scotti, L., Abramovich, D., Pascuali, N., Irusta, G., Meresman, G., Tesone, M., Parborell, F.
Formato:	JOUR
Materias:	Angiogenesis Apoptosis Cell proliferation OHSS Ovary VEGF aflibercept angiogenesis inhibitor claudin 5 Cldn5 protein, rat estradiol Flt1 protein, rat hybrid protein occludin Ocln protein, rat progesterone vascular endothelial growth factor A, rat vasculotropin A vasculotropin receptor vasculotropin receptor 1 vasculotropin receptor 2 unclassified drug vascular endothelial growth factor receptor 1 fc chimera vasculotropin vasculotropin inhibitor animal antagonists and inhibitors apoptosis blood cell proliferation drug effects endothelium cell female metabolism ovary ovary hyperstimulation pathology Sprague Dawley rat animal experiment animal model animal tissue Article controlled study corpus luteum estradiol blood level nonhuman progesterone blood level protein expression protein phosphorylation rat steroidogenesis Angiogenesis Inhibitors Animals Cell Proliferation Claudin-5 Endothelial Cells Estradiol Female Occludin Ovarian Hyperstimulation Syndrome Progesterone Rats, Sprague-Dawley Receptors, Vascular Endothelial Growth Factor Recombinant Fusion Proteins Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 Vascular Endothelial Growth Factor Receptor-2
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_09600760_v144_nPARTB_p392_Scotti
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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