Immunohistochemical analysis of heme oxygenase-1 in preneoplastic and neoplastic lesions during chemical hepatocarcinogenesis

Heme oxygenase (HO) breaks down the pro-oxidant heme into carbon monoxide, iron and the antioxidant biliverdin. The isoform HO-1 plays an effective role to counteract oxidative damage and to control inflammation. Prolonged cellular damage due to chronic inflammation is one of the reasons leading to...

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Detalles Bibliográficos
Autores principales: Caballero, F., Meiss, R., Gimenez, A., Batlle, A., Vazquez, E.
Formato: JOUR
Materias:
Heme oxygenase
Hepatocarcinogenesis
Inflammation
Oxidative stress
p-dimethylaminoazobenzene
4 dimethylaminoazobenzene
antioxidant
biliverdin
carbon dioxide
heme oxygenase 1
iron
animal cell
animal experiment
animal tissue
article
cell damage
cell proliferation
chemical carcinogenesis
chronic inflammation
controlled study
disease course
enzyme localization
epithelium cell
immunohistochemistry
inflammation
Kupffer cell
liver adenoma
liver carcinogenesis
liver cell
liver cell carcinoma
liver injury
liver necrosis
macrophage
male
morphological trait
mouse strain
neoplasm
nonhuman
oxidation
oxidative stress
priority journal
protein expression
rat
tumor differentiation
Western blotting
Adenoma
Animals
Blotting, Western
Carcinoma, Hepatocellular
Disease Progression
Heme Oxygenase (Decyclizing)
Heme Oxygenase-1
Hepatocytes
Immunoenzyme Techniques
Liver
Liver Neoplasms
Macrophages
Male
Membrane Proteins
Mice
Mice, Inbred Strains
Necrosis
p-Dimethylaminoazobenzene
Precancerous Conditions
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09599673_v85_n4_p213_Caballero
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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