Red blood cell aquaporin-1 expression is decreased in hereditary spherocytosis

Aquaporin-1 (AQP1) is the membrane water channel responsible for changes in erythrocyte volume in response to the tonicity of the medium. As the aberrant distribution of proteins in hereditary spherocytosis (HS) generates deficiencies of proteins other than those codified by the mutated gene, we pos...

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Detalles Bibliográficos
Autores principales: Crisp, R.L., Maltaneri, R.E., Vittori, D.C., Solari, L., Gammella, D., Schvartzman, G., García, E., Rapetti, M.C., Donato, H., Nesse, A.
Formato: JOUR
Materias:
Aquaporin-1
Erythropoietin
Serum osmolality
Spherocytosis
ankyrin
aquaporin 1
erythrocyte band 4.1 protein
erythrocyte band 4.2 protein
erythropoietin
spectrin
Article
autoimmune hemolytic anemia
clinical article
controlled study
erythrocyte
erythrocyte membrane
erythrocyte volume
erythroid precursor cell
erythroleukemia cell
flow cytometry
hereditary spherocytosis
human
human cell
polyacrylamide gel electrophoresis
priority journal
protein expression
reticulocyte
serum osmolality
adolescent
adult
biosynthesis
blood
body water
cell line
child
chronic lymphatic leukemia
gene expression regulation
genetics
hemolysis
heterozygote
metabolism
middle aged
osmolarity
osmotic fragility
pathology
preschool child
Spherocytosis, Hereditary
splenectomy
transport at the cellular level
Adolescent
Adult
Anemia, Hemolytic, Autoimmune
Aquaporin 1
Biological Transport
Body Water
Cell Line
Child
Child, Preschool
Erythrocyte Membrane
Erythrocytes
Gene Expression Regulation
Hemolysis
Heterozygote
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Middle Aged
Osmolar Concentration
Osmotic Fragility
Splenectomy
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_09395555_v95_n10_p1595_Crisp
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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