Immunization with recombinant Trypanosoma cruzi ribosomal P2β protein induces changes in the electrocardiogram of immunized mice

Molecular expression cloning techniques revealed that patients with severe chronic Chagas heart disease showed a strong humoral response against the cloned C-terminal portion of the Trypanosoma cruzi ribosomal P2β protein, previously named JL5. The main linear epitope of this polypeptide was mapped...

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Detalles Bibliográficos
Autores principales:	Lopez Bergami, P., Cabeza Meckert, P., Kaplan, D., Levitus, G., Elias, F., Quintana, F., Van Regenmortel, M., Laguens, R., Levin, M.J.
Formato:	JOUR
Materias:	Chagas disease Electrocardiogram Functional assay Heart Immunization Ribosomal P protein Trypanosoma cruzi animal model article chagas disease electrocardiogram enzyme linked immunosorbent assay human humoral immunity immunization mouse nonhuman priority journal trypanosoma cruzi Animals Antibodies, Protozoan Autoantibodies Carrier Proteins Electrocardiography Humans Mice Mice, Inbred BALB C Myocardium Protozoan Proteins Recombinant Fusion Proteins Ribosomal Proteins
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_09288244_v18_n1_p75_LopezBergami
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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