SPECT findings before and after ECT in a patient with major depression and Cotard's syndrome

A patient's major depression and Cotard's syndrome (the delusion of being dead) both resolved completely after 12 ECT treatments. A SPECT study 1 week before ECT showed reduced blood flow in the frontoparietal medial and dorsolateral frontal cortex, basal ganglia, and thalamus; SPECT 1 mon...

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Detalles Bibliográficos
Autores principales: Petracca, G., Migliorelli, R., Vazquez, S., Starkstein, S.E.
Formato: JOUR
Materias:
adult
article
basal ganglion
brain blood flow
case report
cotard syndrome
delusion
depression
electroconvulsive therapy
frontal cortex
frontal lobe
human
male
paranoia
priority journal
single photon emission computer tomography
thalamus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_08950172_v7_n4_p505_Petracca
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:A patient's major depression and Cotard's syndrome (the delusion of being dead) both resolved completely after 12 ECT treatments. A SPECT study 1 week before ECT showed reduced blood flow in the frontoparietal medial and dorsolateral frontal cortex, basal ganglia, and thalamus; SPECT 1 month after ECT showed perfusion increments in those regions. This case study demonstrates that Cotard's syndrome in the context of major depression may be successfully treated with ECT and suggests that the psychiatric improvement was accompanied by increased blood flow in specific brain areas.

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