Activity-dependent reduction of dopamine D2 receptors during a postnatal critical period of plasticity in rat striatum is not affected by prenatal haloperidol treatment

Motor activity induced in the Circling Training test (CT) during a postnatal (PN) critical period of plasticity (PN30-37) produces a long-lasting decrease in the number of binding sites and mRNA expression levels of the dopamine D2 receptor (D2R) in rat striatum. Prenatal exposure to the antipsychot...

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Detalles Bibliográficos
Autores principales: Soiza-Reilly, M., Azcurra, J.M.
Formato: JOUR
Materias:
Critical period of plasticity
Development
Dopamine D2 receptor
Haloperidol
Motor behavior
Striatum
dopamine 2 receptor
haloperidol
messenger RNA
sodium chloride
adulthood
animal experiment
animal tissue
article
binding site
controlled study
corpus striatum
female
gene expression
gestation period
instrumental conditioning
learning
male
motor activity
nerve cell plasticity
nonhuman
ontogeny
perinatal period
prenatal drug exposure
priority journal
progeny
pup (rodent)
rat
receptor binding
Animals
Behavior, Animal
Binding Sites
Corpus Striatum
Dopamine
Dopamine Antagonists
Female
Fetus
Gestational Age
Humans
Male
Motor Activity
Neuronal Plasticity
Pregnancy
Prenatal Exposure Delayed Effects
Random Allocation
Rats
Rats, Sprague-Dawley
Receptors, Dopamine D2
RNA, Messenger
Animalia
Rattus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_07365748_v29_n8_p855_SoizaReilly
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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