B-50/GAP-43 phosphorylation and PKC activity are increased in rat hippocampal synaptosomal membranes after an inhibitory avoidance training

Several lines of evidence indicate that protein kinase C (PKC) is involved in long-term potentiation (LTP) and in certain forms of learning. Recently, we found a learning-specific, time-dependent increase in [3H]phorbol dibutyrate binding to membrane-associated PKC in the hippocampus of rats subject...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Cammarota, M., Paratcha, G., De Stein, M.L., Bernabeu, R., Izquierdo, I., Medina, J.H.
Formato: JOUR
Materias:
B-50/GAP-43
hippocampus
learning
memory
PKC
protein phosphorylation
1 (5 isoquinolinesulfonyl) 2 methylpiperazine
neuromodulin
phorbol dibutyrate
polymyxin B
protein kinase C
protein kinase C inhibitor
staurosporine derivative
tritium
animal cell
animal experiment
article
brain synaptosome
controlled study
enzyme activity
long term potentiation
male
nonhuman
priority journal
rat
synaptic membrane
task performance
training
Animalia
Bovinae
Tritium
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03643190_v22_n4_p499_Cammarota
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares