Inhibition of Junin virus multiplication by caffeine

The inhibitory activity of caffeine, a pharmacologically active compound, on Junin virus (JV) multiplication in Veto cells was evaluated by a virus yield inhibition assay. The compound achieved a dose-dependent inhibition of virus production at concentrations not affecting cell viability. The 50% in...

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Detalles Bibliográficos
Autores principales:	Candurra, N.A., Damonte, E.B.
Formato:	JOUR
Materias:	Antiviral activity Arenaviruses Argentine hemorrhagic fever Caffeine Junin virus caffeine virus protein antivirus agent animal cell antiviral activity article dose response immunofluorescence junin virus nonhuman protein expression vero cell virogenesis animal biosynthesis Cercopithecus drug effect fluorescent antibody technique physiology time Vero cell virus replication Animals Antiviral Agents Cercopithecus aethiops Dose-Response Relationship, Drug Fluorescent Antibody Technique, Indirect Time Factors Vero Cells Viral Proteins Virus Replication
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03257541_v31_n3_p135_Candurra
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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