Role of the cell heterogeneity in Haemostasis regulation

The endothelium is an organ that is involved in several physiological processes, mainly blood fluid preservation. Non-activated endothelial cells express an anticoagulant, antiadhesive and vasodilative phenotype, whereas activated endothelial cells express procoagulant, proadhesive and vasoconstrict...

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Autor principal: Duboscq, C.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03252957_v40_n3_p_Duboscq
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Sumario:The endothelium is an organ that is involved in several physiological processes, mainly blood fluid preservation. Non-activated endothelial cells express an anticoagulant, antiadhesive and vasodilative phenotype, whereas activated endothelial cells express procoagulant, proadhesive and vasoconstrictive properties. The structure and function are regulated in space and time and this fact originates a specific vascular bed haemostasis . The objective of this work is to review the new concepts in endothelial cell heterogeneity and their influence in haemostasis regulation. © 2007 Federación Bioquímica de la Provincia de Buenos Aires.