Mechanisms of synaptic alteration mediated by antibodies from patients with amyotrophic lateral sclerosis

Background: Sporadic amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting particularly motoneurons. Several pieces of evidence suggested the involvement of autoimmune mechanisms mediated by antibodies in ALS. However, the significance of those antibodies in the disease and th...

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Detalles Bibliográficos
Autores principales:	Pagani, M.R., Reisin, R.C., Uchitel, O.D.
Formato:	JOUR
Materias:	Calcium channels Calcium homeostasis alteration IP3R Phospholipase C RyR Signaling mechanisms calcium channel immunoglobulin G phospholipase C ryanodine receptor amyotrophic lateral sclerosis article calcium homeostasis electrophysiology human immunohistochemistry immunoreactivity motor nerve nerve ending synaptic transmission
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03250938_v32_n1_p9_Pagani
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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