Neuroprotective effects of estradiol in hippocampal neurons and glia of middle age mice

During aging the hippocampus experiences structural, molecular, and functional alterations. Protection from age-related disorders is provided by several factors, including estrogens. Since aging defects start at middle age, we studied if 17 β-estradiol (E2) protected the hippocampus at this age peri...

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Detalles Bibliográficos
Autores principales:	Saravia, F., Beauquis, J., Pietranera, L., De Nicola, A.F.
Formato:	JOUR
Materias:	5-bromo-2′-deoxyuridine (BrdU) Brain aging Dentate gyrus doublecortin Estradiol Glial fibrillary acidic protein (GFAP) Hilar neurons Ki67 Lipofuscin Neurogenesis Neuroprotection broxuridine cholesterol estradiol animal cell animal experiment animal tissue article astrocytosis cell density cell differentiation cell loss cell migration cell proliferation controlled study dentate gyrus glia hippocampus immunocytochemistry male mouse nerve cell nervous system development neuroprotection nonhuman priority journal stem cell Aging Animals Cell Death Cell Differentiation Hippocampus Immunohistochemistry Male Mice Neuroglia Neurons Neuroprotective Agents Sex Factors Stem Cells
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03064530_v32_n5_p480_Saravia
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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