Progesterone attenuates demyelination and microglial reaction in the lysolecithin-injured spinal cord

Progesterone treatment of mice with experimental autoimmune encephalomyelitis has shown beneficial effects in the spinal cord according to enhanced clinical, myelin and neuronal-related parameters. In the present work, we report progesterone effects in a model of primary demyelination induced by the...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Garay, L., Tüngler, V., Deniselle, M.C.G., Lima, A., Roig, P., De Nicola, A.F.
Formato:	JOUR
Materias:	Demyelination Lysolecithin Microglial reaction Progesterone Remyelination CD11b antigen lysophosphatidylcholine messenger RNA myelin basic protein progesterone animal experiment animal model animal tissue antiinflammatory activity article cell density controlled study demyelination dorsal root drug effect drug implant macrophage male microglia mouse myelination neural stem cell nonhuman oligodendroglia priority journal single drug dose spinal cord injury Animals Demyelinating Diseases Disease Models, Animal Immunohistochemistry Lysophosphatidylcholines Male Mice Mice, Inbred C57BL Microglia Spinal Cord
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03064522_v192_n_p588_Garay
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Progesterone attenuates demyelination and microglial reaction in the lysolecithin-injured spinal cord
Publicado: (2011)

Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord
Publicado: (2006)

Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord
por: Labombarda, F., et al.

Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin
Publicado: (2006)

Remyelination after cuprizone-induced demyelination in the rat is stimulated by apotransferrin
por: Adamo, A.M., et al.

Cuprizone-Induced demyelination in CNP::GFP transgenic mice
Publicado: (2010)

Cuprizone-Induced demyelination in CNP::GFP transgenic mice
por: Silvestroff, L., et al.

Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons
Publicado: (2005)

Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons
por: Gonzalez, S.L., et al.

Progesterone reduces secondary damage, preserves white matter, and improves locomotor outcome after spinal cord contusion
Publicado: (2014)

Progesterone reduces secondary damage, preserves white matter, and improves locomotor outcome after spinal cord contusion
por: Garcia-Ovejero, D., et al.

Steroid Effects on Glial Cells: Detrimental or Protective for Spinal Cord Function?
Publicado: (2003)

Steroid Effects on Glial Cells: Detrimental or Protective for Spinal Cord Function?
por: De Nicola, A.F., et al.

Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord
Publicado: (2004)

Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord
por: González, S.L., et al.

Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease
Publicado: (2005)

Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease
por: Gonzalez Deniselle, M.C., et al.

Local synthesis and dual actions of progesterone in the nervous system: Neuroprotection and myelination
Publicado: (2004)

Local synthesis and dual actions of progesterone in the nervous system: Neuroprotection and myelination
por: Schumacher, M., et al.

Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration
Publicado: (2010)

Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration
por: Meyer, M., et al.

Effects of Progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury
Publicado: (2009)

Effects of Progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury
por: Labombarda, F., et al.

Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis
Publicado: (2012)

Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis
por: Garay, L.I., et al.

Spinal cord the official journal of the International Medical Society of Paraplegia.
Publicado: (1996)

Effect of transferrin on hypomyelination induced by iron deficiency
Publicado: (2008)

Effect of transferrin on hypomyelination induced by iron deficiency
por: Badaracco, M.E., et al.

Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration
Publicado: (2009)

Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration
por: De Nicola, A.F., et al.

Dexamethasone up-regulates mRNA for Na+,K+-ATPase in some spinal cord neurones after cord transection
Publicado: (1996)

Dexamethasone up-regulates mRNA for Na+,K+-ATPase in some spinal cord neurones after cord transection
por: Gonzalez, S., et al.

Progesterone effects on neuronal ultrastructure and expression of microtubule-associated protein 2 (MAP2) in bats with acute spinal cord injury
Publicado: (2009)

Progesterone effects on neuronal ultrastructure and expression of microtubule-associated protein 2 (MAP2) in bats with acute spinal cord injury
por: González, S.L., et al.

Steroid protection in the experimental autoimmune encephalomyelitis model of multiple sclerosis
Publicado: (2008)

Steroid protection in the experimental autoimmune encephalomyelitis model of multiple sclerosis
por: Garay, L., et al.

Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function
por: Croci Russo, Diego Omar
Publicado: (2011)

Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function
por: Pasquini, L.A., et al.
Publicado: (2011)

Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function
por: Pasquini, L.A., et al.

Galectin-3 drives oligodendrocyte differentiation to control myelin integrity and function
por: Pasquini, L.A., et al.
Publicado: (2011)