Midazolam disrupts fear memory reconsolidation

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The current research examines the influence of midazolam (MDZ) on memory reconsolidation using a contextual fear paradigm in rats, based on three context-shock training trials (0.7 mA, 3 s). First, we evaluate the effect of MDZ (1 mg/kg, i.p.) injected shortly after the training procedure. Second, w...

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Detalles Bibliográficos
Autores principales: Bustos, S.G., Maldonado, H., Molina, V.A.
Formato: JOUR
Materias:
benzodiazepine
contextual aversive conditioning
GABA-A receptors
reminder
retrograde amnesia
4 aminobutyric acid A receptor
midazolam
benzodiazepine receptor affecting agent
animal experiment
article
conditioning
controlled study
drug effect
environmental factor
fear
freezing
male
memory consolidation
nonhuman
photoreactivation
priority journal
rat
scoring system
stimulus response
training
animal
brain
conditioned reflex
electric shock
learning
long term memory
memory
physiology
time
Wistar rat
Animals
Association Learning
Brain
Conditioning, Classical
Electroshock
Fear
GABA Modulators
Male
Memory
Midazolam
Rats
Rats, Wistar
Retention (Psychology)
Time Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_03064522_v139_n3_p831_Bustos
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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