Effect of fatty acids on arenavirus replication: Inhibition of virus production by lauric acid

To study the functional involvement of cellular membrane properties on arenavirus infection, saturated fatty acids of variable chain length (C10-C18) were evaluated for their inhibitory activity against the multiplication of Junin virus (JUNV). The most active inhibitor was lauric acid (C12), which...

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Detalles Bibliográficos
Autores principales:	Bartolotta, S., García, C.C., Candurra, N.A., Damonte, E.B.
Formato:	JOUR
Materias:	Arenavirus cell membrane cell stimulation Junin virus lauric acid saturated fatty acid triacylglycerol virion virus glycoprotein virus infection virus protein virus replication Animals Cell Line Cercopithecus aethiops Dose-Response Relationship, Drug Fatty Acids Inhibitory Concentration 50 Lauric Acids Membrane Glycoproteins Microbial Sensitivity Tests Triglycerides Vero Cells Viral Proteins Virion Virus Replication
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03048608_v146_n4_p777_Bartolotta
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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