Effect of bitter compounds on amylase secretion in murine submandibular glands: Signaling pathway mechanisms

Background: Amylase is synthesized in submandibular glands (SMG) and released into the oral cavity to degrade carbohydrates in the mouth. Bitter taste receptors (T2R) belong to the G-protein coupled receptor (GPCR) family and are expressed in the taste cells and also in the digestive tract. Methods:...

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Detalles Bibliográficos
Autores principales:	Dasso, M., Pagotto, R., Pignataro, O.P., Diez, R.A., Sales, M.E.
Formato:	JOUR
Materias:	Amylase Bitter agonist cAMP Gi protein Inositol monophosphate Protein kinase A amylase cyclic AMP cyclic AMP dependent protein kinase cycloheximide denatonium benzoate guanine nucleotide binding protein gustducin inhibitory guanine nucleotide binding protein inositol phosphate phospholipase C beta2 theophylline unclassified drug animal tissue article bitter taste controlled study enzyme activity enzyme inhibition enzyme linked immunosorbent assay enzyme localization enzyme release immunohistochemistry mouse nonhuman priority journal protein expression protein function quantitative analysis radioimmunoassay signal transduction submandibular gland taste bud Western blotting Amylases Animals Blotting, Western Cyclic AMP Immunohistochemistry Mice Mice, Inbred BALB C Signal Transduction Submandibular Gland Murinae
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_03044165_v1810_n12_p1212_Dasso
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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