Response of glucose metabolism enzymes in an acute porphyria model: Role of reactive oxygen species

Acute hepatic porphyrias are human metabolic diseases characterized by the accumulation of heme precursors, such as 5-aminolevulinic acid (ALA). The administration of glucose can prevent the symptomatology of these diseases. The aim of this work was to study the relationship between glucose metaboli...

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Detalles Bibliográficos
Autores principales: Lelli, S.M., De Viale, L.C.S.M., Mazzetti, M.B.
Formato: JOUR
Materias:
Acute porphyria model
Glucose metabolism
Rat liver
Reactive oxygen species
1,4 dihydro 2,4,6 trimethyl 3,5 pyridinedicarboxylic acid diethyl ester
5 aminolevulinate synthase
allylisopropylacetamide
aminolevulinic acid
carbonyl derivative
catalase
corn oil
ferrochelatase
glycogen phosphorylase
liver protein
phosphoenolpyruvate carboxykinase (GTP)
porphobilinogen
reactive oxygen metabolite
sodium chloride
superoxide dismutase
acute intermittent porphyria
animal experiment
animal model
animal tissue
article
chemoluminescence
controlled study
enzyme activity
enzyme induction
female
glucose metabolism
lipid peroxidation
liver level
nonhuman
oxidative stress
priority journal
rat
Allylisopropylacetamide
Animals
Chemiluminescent Measurements
Dicarbethoxydihydrocollidine
Disease Models, Animal
Female
Glucose
Heme
Lipid Peroxidation
Liver
Porphyria, Acute Intermittent
Rats
Rats, Wistar
Reactive Oxygen Species
Urine
Animalia
Rattus norvegicus
Zea mays
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0300483X_v216_n1_p49_Lelli
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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