Authentic cell-specific and developmentally regulated expression of pro- opiomelanocortin genomic fragments in hypothalamic and hindbrain neurons of transgenic mice

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The pro-opiomelanocortin (POMC) gene is expressed in a subset of hypothalamic and hindbrain neurons and in pituitary melanotrophs and corticotrophs. POMC neurons release the potent opioid β-endorphin and several active melanocortins that control homeostasis and feeding behavior. POMC gene expression...

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Detalles Bibliográficos
Autores principales: Young, J.I., Otero, V., Cerdán, M.G., Falzone, T.L., Cheng Chan, E., Low, M.J., Rubinstein, M.
Formato: JOUR
Materias:
β- endorphin
Arcuate nucleus
Gene expression
Hypothalamus
Melanocortin
Neuron-specific expression
Pituitary
Pro-opiomelanocortin
Transgenic mice
melanocortin
animal cell
animal experiment
animal tissue
article
cell specificity
gene amplification
gene deletion
gene expression regulation
gene library
gene location
genome
hormonal regulation
hypothalamus
in situ hybridization
nonhuman
plasmid
polymerase chain reaction
priority journal
rhombencephalon
transgenic mouse
Animals
DNA Fragmentation
Gene Expression Regulation, Developmental
Genome
Mice
Mice, Transgenic
Neurons
Organ Specificity
Pro-Opiomelanocortin
Rhombencephalon
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_02706474_v18_n17_p6631_Young
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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