Anti-melanoma vaccinal capacity of CD11c-positive and -negative cell populations present in GM-CSF cultures derived from murine bone marrow precursors

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We have initially shown that DC/ApoNec vaccine can induce protection against the poorly immunogenic B16F1 melanoma in mice. The population of DC obtained for vaccination after 7. days culture with murine GM-CSF is heterogeneous and presents about 60% of CD11c+ DC. Therefore, our purpose was to ident...

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Detalles Bibliográficos
Autores principales: Campisano, S., Mac Keon, S., Gazzaniga, S., Ruiz, M.S., Traian, M.D., Mordoh, J., Wainstok, R.
Formato: JOUR
Materias:
Bone marrow
Dendritic cell
Melanoma
Vaccine
apoptotic and necrotic cell vaccine
B7 antigen
CD11b antigen
CD83 antigen
CD86 antigen
dendritic cell vaccine
glycoprotein p 15095
granulocyte macrophage colony stimulating factor
interleukin 12
major histocompatibility antigen class 2
unclassified drug
vaccine
animal cell
animal experiment
animal model
article
bone marrow
cell differentiation
cell fractionation
cell population
cell type
coculture
controlled study
dendritic cell
immunogenicity
macrophage
male
mouse
neutrophil
nonhuman
phagocyte
phenotype
precursor
priority journal
tumor cell
Animals
Antigen Presentation
Antigens, CD11c
Antigens, Surface
Bone Marrow Cells
Cancer Vaccines
Cell Differentiation
Cell Line, Tumor
Coculture Techniques
Dendritic Cells
Granulocyte-Macrophage Colony-Stimulating Factor
Interleukin-12
Lymphocyte Activation
Male
Melanoma, Experimental
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Neutrophils
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0264410X_v31_n2_p354_Campisano
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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