Fibroblast growth factor-2 in hyperplastic pituitaries of D2R knockout female mice

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Dopamine D2 receptor (D2R) knockout (KO) female mice develop chronic hyperprolactinemia and pituitary hyperplasia. Our objective was to study the expression of the mitogen fibroblast growth factor (FGF2) and its receptor, FGFR1, comparatively in pituitaries from KO and wild-type (WT) female mice. We...

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Autores principales:	Cristina, C., Díaz-Torga, G., Góngora, A., Guida, M.C., Perez-Millán, M.I., Baldi, A., Becu-Villalobos, D.
Formato:	JOUR
Materias:	Dopaminergic D2 receptor Extracellular signal-regulated kinase phosphorylation Fibroblast growth factor receptor-1 Immunohistochemistry Prolactin dopamine 2 receptor fibroblast growth factor 2 prolactin animal cell animal cell culture animal experiment animal model animal tissue article cell assay cell proliferation cellular distribution chronic disease concentration (parameters) controlled study cytosol DNA synthesis enzyme linked immunosorbent assay enzyme phosphorylation female genotype hyperpituitarism hyperprolactinemia hypophysis function immunofluorescence immunohistochemistry knockout mouse mouse nonhuman priority journal prognosis prolactin release prolactinoma protein localization protein secretion reliability species comparison Western blotting wild type Animals Blotting, Western Cell Growth Processes Enzyme-Linked Immunosorbent Assay Extracellular Signal-Regulated MAP Kinases Female Fibroblast Growth Factor 2 Hyperplasia Mice Mice, Inbred C57BL Mice, Knockout Microscopy, Confocal Microscopy, Fluorescence Phosphorylation Pituitary Gland, Anterior Prolactinoma Receptor, Fibroblast Growth Factor, Type 1 Receptors, Dopamine D2
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_01931849_v293_n5_pE1341_Cristina
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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