Desensitization of angiotensin II: Effect on [Ca2+]i, inositol triphosphate, and prolactin in pituitary cells

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Activation of pituitary angiotensin (ANG II) type 1 receptors (AT1) mobilizes intracellular Ca2+, resulting in increased prolactin secretion. We first assessed desensitization of AT1 receptors by testing ANG II-induced intracellular Ca2+ concentration ([Ca2+]i) response in rat anterior pituitary cel...

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Detalles Bibliográficos
Autores principales: Iglesias, A.G., Suärez, C., Feierstein, C., Díaz-Torga, G., Becu-Villalobos, D., Becü-Villalobos, D.
Formato: JOUR
Materias:
Angiotensin type 1 receptor
Calcium
Homologous desensitization
Protein kinase C
Thyrotropin-releasing hormone
angiotensin
angiotensin 1 receptor
calcium ion
inositol trisphosphate
ionomycin
prolactin
protein kinase C
protirelin
animal cell
animal experiment
article
calcium cell level
calcium mobilization
concentration response
controlled study
desensitization
enzyme activation
female
hypophysis cell
nonhuman
priority journal
prolactin release
Angiotensin II
Animals
Cells, Cultured
Drug Tolerance
Female
Inositol 1,4,5-Trisphosphate
Ionomycin
Pituitary Gland, Anterior
Prolactin
Protein Kinase C
Rats
Rats, Sprague-Dawley
Receptor, Angiotensin, Type 1
Receptor, Angiotensin, Type 2
Receptors, Angiotensin
Tetradecanoylphorbol Acetate
Thyrotropin-Releasing Hormone
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01931849_v280_n343-3_pE462_Iglesias
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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