Antidiuretic responses to osmotic cutaneous stimulation in the toad, Bufo arenarum - A possible adaptive control mechanism for urine production
Osmotic stimulation of the skin of the toad Bufo arenarum with isotonic (115 m M) or hypertonic (400 m M) NaCl solutions produced a marked and reversible antidiuresis within 5 min. No changes in plasma osmolarity were detected in the course of this response. Hypophysectomized animals exhibited a low...
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| Autores principales: | , , , |
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_01741578_v159_n1_p91_Petriella |
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| Sumario: | Osmotic stimulation of the skin of the toad Bufo arenarum with isotonic (115 m M) or hypertonic (400 m M) NaCl solutions produced a marked and reversible antidiuresis within 5 min. No changes in plasma osmolarity were detected in the course of this response. Hypophysectomized animals exhibited a lower and delayed antidiuresis when exposed to a hypertonic environment (400 m M NaCl). This antidiuretic response was drastically reduced in normal toads after ten consecutive days of administration of the sympatoplexic guanethidine. The existence of a feed-forward control of urine production initiated by cutaneous osmotic sensors and involving an adrenergic component is proposed. © 1989 Springer-Verlag. |
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