Changes in antiviral susceptibility to entry inhibitors and endocytic uptake of dengue-2 virus serially passaged in Vero or C6/36 cells

The aim of the present study was to analyze the influence of virus origin, mammalian or mosquito cell-derived, on antiviral susceptibility of DENV-2 to entry inhibitors and the association of this effect with any alteration in the mode of entry into the cell. To this end, ten serial passages of DENV...

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Detalles Bibliográficos
Autores principales: Acosta, E.G., Piccini, L.E., Talarico, L.B., Castilla, V., Damonte, E.B.
Formato: JOUR
Materias:
Antiviral activity
Carrageenan
Clathrin-mediated endocytosis
Dengue virus
Entry inhibitor
Sulfated polysaccharide
carrageenan
chlorpromazine
heparin
antivirus agent
virus RNA
antiviral activity
antiviral susceptibility
article
controlled study
Dengue virus 1
Dengue virus 2
endocytosis
host cell
in vitro study
nonhuman
priority journal
Vero cell
virus entry
adaptation
animal
antiviral resistance
cell line
Chlorocebus aethiops
DNA sequence
drug effects
genetics
growth, development and aging
molecular genetics
mosquito
nucleotide sequence
viral plaque assay
virus culture
Adaptation, Biological
Animals
Antiviral Agents
Cell Line
Cercopithecus aethiops
Culicidae
Dengue Virus
DNA Mutational Analysis
Drug Resistance, Viral
Endocytosis
Heparin
Molecular Sequence Data
RNA, Viral
Sequence Analysis, DNA
Serial Passage
Viral Plaque Assay
Virus Internalization
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01681702_v184_n_p39_Acosta
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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