Mammary differentiation induces expression of Tristetraprolin, a tumor suppressor AU-rich mRNA-binding protein

Tristetraprolin (TTP) is a RNA-binding protein that inhibits the expression of pro-inflammatory cytokines and invasiveness-associated genes. TTP levels are decreased in many different cancer types and it has been proposed that this protein could be used as a prognostic factor in breast cancer. Here,...

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Detalles Bibliográficos
Autores principales: Goddio, M.V., Gattelli, A., Slomiansky, V., Lacunza, E., Gingerich, T., Tocci, J.M., Facchinetti, M.M., Curino, A.C., LaMarre, J., Abba, M.C., Kordon, E.C.
Formato: JOUR
Materias:
Breast cancer
Lactation
Mammary gland
Prolactin
Tristetraprolin
messenger RNA
prolactin
RNA binding protein
STAT5a protein
tristetraprolin
3' untranslated region
animal tissue
article
AU rich element
breast cancer
breast carcinoma
breast cell
breast lesion
breast tumor
cancer cell
cancer grading
cancer invasion
cell proliferation
controlled study
DNA microarray
gene expression
human
human tissue
immunohistochemistry
lactation
mammary gland
mouse
nonhuman
priority journal
protein expression
reverse transcription polymerase chain reaction
serial analysis of gene expression
tissue differentiation
Animals
Base Sequence
Breast Neoplasms
Cell Differentiation
Cell Line, Tumor
Female
Gene Expression Regulation, Neoplastic
Humans
Mammary Glands, Animal
Mammary Glands, Human
Mammary Neoplasms, Animal
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Pregnancy
STAT5 Transcription Factor
Tumor Suppressor Proteins
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01676806_v135_n3_p749_Goddio
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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