Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha

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The placenta produces a wide number of molecules that play essential roles in the establishment and maintenance of pregnancy. In this context, leptin has emerged as an important player in reproduction. The synthesis of leptin in normal trophoblastic cells is regulated by different endogenous biochem...

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Detalles Bibliográficos
Autores principales: Gambino, Y.P., Pérez Pérez, A., Dueñas, J.L., Calvo, J.C., Sánchez-Margalet, V., Varone, C.L.
Formato: JOUR
Materias:
17β-estradiol
Estrogen receptor
Gene expression
Leptin
Placenta
estradiol
estrogen receptor alpha
leptin
mitogen activated protein kinase
protein kinase B
article
controlled study
enzyme activation
hormonal regulation
hormone action
hormone synthesis
human
human cell
placenta
priority journal
Cell Membrane
Cell Nucleus
Estradiol
Estrogen Receptor alpha
Female
Gene Expression Regulation
Gene Silencing
Humans
Models, Biological
Pregnancy
Protein Binding
Protein Transport
Serum Albumin, Bovine
Signal Transduction
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01674889_v1823_n4_p900_Gambino
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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