Characterization of the Trypanosoma cruzi Cdc2p-related protein kinase 1 and identification of three novel associating cyclins

Several Cdc2p-related protein kinases (CRKs) have been described in trypanosomatids but their role in the control of the cell cycle nor their biological functions have been addressed. In Trypanosoma cruzi two CRKs have been identified, TzCRK1 and TzCRK3. In this work we further characterize T. cruzi...

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Detalles Bibliográficos
Autores principales: Gómez, E.B., Santori, M.I., Laría, S., Engel, J.C., Swindle, J., Eisen, H., Szankasi, P., Téllez-Ión, M.T.
Formato: JOUR
Materias:
Cdc2p-related kinases
Cell cycle
Cyclins
Kinetoplast
Trypanosoma cruzi
Two-hybrid system
cyclin dependent kinase
cyclin dependent kinase inhibitor
cycline
flavopiridol
mitochondrial DNA
olomoucine
protein kinase
protein kinase inhibitor
article
cell cycle
cell organelle
cellular distribution
controlled study
enzyme activity
enzyme inhibition
epimastigote
immunoprecipitation
nonhuman
priority journal
protein analysis
protein localization
protein protein interaction
Amino Acid Sequence
Animals
CDC2 Protein Kinase
CDC2-CDC28 Kinases
Cyclin-Dependent Kinases
Cytoplasm
Enzyme Inhibitors
Flavonoids
Histones
Immunoglobulin G
Immunohistochemistry
Kinetin
Mitochondria
Molecular Sequence Data
Piperidines
Precipitin Tests
Protein Kinases
Protozoan Proteins
Purines
Retinoblastoma Protein
Sequence Alignment
Trypanosoma
Trypanosomatidae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_01666851_v113_n1_p97_Gomez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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