The SSRI fluoxetine exhibits mild effects on the reproductive axis in the cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes)

Among the wide variety of pharmaceuticals released into the environment, Fluoxetine (FLX), a selective serotonin reuptake inhibitor, is one of the most prescribed for the treatment of major depression. It inhibits serotonin (5-HT) reuptake at the presinaptic membrane, increasing serotonergic activit...

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Detalles Bibliográficos
Autores principales: Dorelle, L.S., Da Cuña, R.H., Rey Vázquez, G., Höcht, C., Shimizu, A., Genovese, G., Lo Nostro, F.L.
Formato: JOUR
Materias:
Contaminants of emerging concern
Endocrine disruption
Gonadotrophins
Pharmaceuticals
Reproduction
Serotonin
Controlled drug delivery
Drug products
Fish
Physiology
Contaminants of emerging concerns
Endocrine disrupters
alcian blue
estradiol
fluoxetine
follitropin beta subunit
luteinizing hormone beta subunit
sodium chloride
testosterone
vitellogenin
endocrine disruptor
serotonin uptake inhibitor
steroid
water pollutant
chemical compound
cichlid
drug
hormone
inhibitor
physiology
pollutant
protein
reproduction
adult
animal experiment
animal tissue
Article
Cichlasoma dimerus
controlled study
estradiol blood level
female
foam cell
follitropin blood level
hypophysis
luteinizing hormone blood level
male
Neotropics
nonhuman
ovary tissue
reproductive toxicity
serotoninergic system
testosterone blood level
animal
drug effects
ecotoxicology
metabolism
toxicity
Cichlasoma
Cichlidae
Teleostei
Vertebrata
Animals
Cichlids
Ecotoxicology
Endocrine Disruptors
Female
Fluoxetine
Male
Pituitary Gland
Serotonin Uptake Inhibitors
Steroids
Water Pollutants, Chemical
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00456535_v171_n_p370_Dorelle
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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