Distributive pairing and aneuploidy in man
The extrapolation of the "distributive-pairing hypothesis" of meiosis in Drosophila melanogaster females to human gametogenesis is proposed to account for the co-occurrence of rare karyotype abnormalities in human families. A description of the hypothesis is presented with its application...
| Autores principales: | , |
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00368075_v145_n3627_p66_Grell |
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| Sumario: | The extrapolation of the "distributive-pairing hypothesis" of meiosis in Drosophila melanogaster females to human gametogenesis is proposed to account for the co-occurrence of rare karyotype abnormalities in human families. A description of the hypothesis is presented with its application to some established cases in the cytogenetic literature. |
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