Effect of caffeine on the memory of the mouse

Albino mice were injected i.p. with caffeine (27.9 mg/kg) 10 min pre-trial. The mice had no trial retention (300-s period) after 24h. This result suggests that caffeine, at this dose, would upsets some mechanism involved in memory processes. No correlation is observed between serotonin (5-HT) increa...

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Detalles Bibliográficos
Autores principales: Izquierdo, J.A., Costas, S.M., Adolfo Justel, E., Rabiller, G.
Formato: JOUR
Materias:
Caffeine
Memory
Passive avoidance test
Serotonin
caffeine
animal experiment
avoidance behavior
central nervous system
conditioning
drug response
intraperitoneal drug administration
memory
mouse
passive avoidance
serotoninergic system
Animal
Brain Stem
Male
Mice
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00333158_v61_n1_p29_Izquierdo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Albino mice were injected i.p. with caffeine (27.9 mg/kg) 10 min pre-trial. The mice had no trial retention (300-s period) after 24h. This result suggests that caffeine, at this dose, would upsets some mechanism involved in memory processes. No correlation is observed between serotonin (5-HT) increase and caffeine's effect on retention. © 1979 Springer-Verlag.

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