Changes in gamma-aminobutyric acid high affinity binding to cerebral cortex membranes after pinealectomy or melatonin administration to rats1

In order to assess the effect of pinealectomy (Px) on the diurnal rhythmicity of gamma-aminobutyric acid (GABA) high affinity binding to cerebral cortex membranes, groups of intact. Px or sham Px rats (subjected to surgery 15 days earlier) were killed at six different time intervals during the 24-ho...

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Detalles Bibliográficos
Autores principales: Castroviejo, D.A., Rosenstein, R.E., Romeo, H.E., Cardinali, D.P.
Formato: JOUR
Materias:
Cerebral cortex
GABA binding
Melatonin
Pineal gland
Superior cervical ganglion
4 aminobutyric acid
melatonin
radioisotope
4 aminobutyric acid h 3
animal cell
autonomic nervous system
brain cortex
central nervous system
drug efficacy
drug receptor binding
endocrine system
nervous system
nonhuman
pharmacokinetics
pineal body
priority journal
rat
superior cervical ganglion
synaptosome
Animal
Binding Sites
Cell Membrane
Cerebral Cortex
Circadian Rhythm
Dose-Response Relationship, Drug
gamma-Aminobutyric Acid
Injections, Subcutaneous
Kinetics
Male
Nerve Crush
Pineal Gland
Rats
Rats, Inbred Strains
Subcellular Fractions
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00283835_v43_n1_p24_Castroviejo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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