Multifocal motor neuropathy. Immediate response to intravenous immunoglobulin

Multifocal motor neuropathy, a rare insidious immune-mediated disorder, features muscular weakness and atrophy, as well as arreflexia, due to nerve conduction block and is often associated with the presence of anti-GM1antibody. We report a patient with a nine-year history of progressive upper limb w...

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Autores principales: Cammarota, A., Nogues, M., Rivero, A., Garcia, H.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00257680_v61_n4_p441_Cammarota
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Sumario:Multifocal motor neuropathy, a rare insidious immune-mediated disorder, features muscular weakness and atrophy, as well as arreflexia, due to nerve conduction block and is often associated with the presence of anti-GM1antibody. We report a patient with a nine-year history of progressive upper limb weakness, misdiagnosed as amyotrophic lateral sclerosis, who responded within hours to intravenous immunoglobulin treatment with full recovery of muscle strength. This case highlights the need to search for conduction block in patients with lower motor neuron involvement.