Stability study on renal type I mineralocorticoid receptor

The purpose of this work is to review stability and activation properties of type 1 receptor, in order to explain the reasons for its extreme in vitro instability. We demonstrate that the treatment of rat kidney cytosol with H2O2 prevents aldosterone binding, DNA/steroid- receptor complex interactio...

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Detalles Bibliográficos
Autor principal:	Galigniana, M.D.
Formato:	JOUR
Materias:	mineralocorticoid receptor oxidation stability thiol groups 5,5' dithiobis(2 nitrobenzoic acid) aldosterone DNA edetic acid egtazic acid hydrogen peroxide iron mercaptoethanol n ethylmaleimide steroid thiol group animal cell article cell free system cytosol DNA binding high temperature procedures kidney nonhuman rat receptor binding thermostability Animalia
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00243205_v59_n7_p511_Galigniana
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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