Influence of phosphatase inhibitors and nucleotides on [3H]dexamethasone binding in cytosol of human placenta

The purpose of this investigation was to establish the properties of [3H]dexamethasone binding sites in cytosol of human placenta at term. Cytosol containing 20 mM sodium molybdate (MoO4Na2) was incubated for 120min at 20°C with 40 nM [3H]dexamethasone. The following properties were observed: (a) a...

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Detalles Bibliográficos
Autores principales: Heller, C., Coirini, H., de Nicola, A.F.
Formato: JOUR
Materias:
11beta hydroxysteroid dehydrogenase
4 nitrophenyl phosphate
acid phosphatase
adenosine triphosphate
alkaline phosphatase
cortisone
cyclic amp
cyclic gmp
dexamethasone
estradiol
fluoride sodium
glucocorticoid receptor
guanosine triphosphate
hydrocortisone
isobutylmethylxanthine
molybdate sodium
nucleotide
phosphatase
progesterone
radioisotope
testosterone
dexamethasone h 3
drug analysis
drug antagonism
drug comparison
drug identification
drug interaction
drug isolation
drug protein binding
female genital system
human
human cell
hydrocortisone h 3
inhibitor
normal human
placenta
pregnancy
priority journal
Acid Phosphatase
Alkaline Phosphatase
Binding, Competitive
Cytosol
Dexamethasone
Female
Human
Kinetics
Molybdenum
Placenta
Pregnancy
Receptors, Glucocorticoid
Receptors, Steroid
Ribonucleotides
Sodium Fluoride
Support, Non-U.S. Gov't
Tungsten
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00224731_v21_n4_p381_Heller
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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