Modulation of GABA release from the thalamic reticular nucleus by cocaine and caffeine: Role of serotonin receptors

Serotonin receptors are targets of drug therapies for a variety of neuropsychiatric and neurodegenerative disorders. Cocaine inhibits the re-uptake of serotonin (5-HT), dopamine, and noradrenaline, whereas caffeine blocks adenosine receptors and opens ryanodine receptors in the endoplasmic reticulum...

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Detalles Bibliográficos
Autores principales:	Goitia, B., Rivero-Echeto, M.C., Weisstaub, N.V., Gingrich, J.A., Garcia-Rill, E., Bisagno, V., Urbano, F.J.
Formato:	JOUR
Materias:	caffeine cocaine GABA serotonin thalamic reticular nucleus 1 (2 methoxyphenyl) 4 (4 phthalimidobutyl)piperazine adenosine serotonin 1A receptor serotonin 2A receptor serotonin receptor 4 aminobutyric acid cadmium chloride dopamine uptake inhibitor inositol 1,4,5 trisphosphate phosphodiesterase inhibitor phospholipase C serotonin receptor affecting agent 4 aminobutyric acid release animal experiment animal tissue Article concentration (parameters) controlled study excitatory postsynaptic potential GABAergic transmission inhibition kinetics male mouse neuromodulation nonhuman pharmacological blocking priority journal serotoninergic system thalamus reticular nucleus thalamus ventral nucleus whole cell patch clamp action potential animal dose response drug effects genetics in vitro study knockout mouse metabolism patch clamp technique thalamus nucleus Action Potentials Animals Cadmium Chloride Caffeine Cocaine Dopamine Uptake Inhibitors Dose-Response Relationship, Drug gamma-Aminobutyric Acid In Vitro Techniques Inositol 1,4,5-Trisphosphate Male Mice Mice, Knockout Patch-Clamp Techniques Phosphodiesterase Inhibitors Receptor, Serotonin, 5-HT2A Serotonin Serotonin Agents Thalamic Nuclei Type C Phospholipases
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00223042_v136_n3_p526_Goitia
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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