Thyroid status modulates T lymphoma growth via cell cycle regulatory proteins and angiogenesis

We have shown in vitro that thyroid hormones (THs) regulate the balance between proliferation and apoptosis of T lymphoma cells. The effects of THs on tumor development havebeen studied, but the results are still controversial.Herein,weshowthemodulatory action of thyroid status on the in vivo growth...

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Detalles Bibliográficos
Autores principales:	Sterle, H.A., Valli, E., Cayrol, F., Paulazo, M.A., Martinel Lamas, D.J., Diaz Flaqué, M.C., Klecha, A.J., Colombo, L., Medina, V.A., Cremaschi, G.A., Barreiro Arcos, M.L.
Formato:	JOUR
Materias:	Angiogenesis Cell cycle T lymphoma Thyroid hormones beta 2 microglobulin caspase 3 cyclin A2 cyclin B1 cyclin D1 cyclin D2 cyclin D3 cyclin dependent kinase inhibitor 1 cyclin dependent kinase inhibitor 1B cyclin dependent kinase inhibitor 2A cyclin dependent kinase inhibitor 2B cyclin E liothyronine phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase protein p53 retinoblastoma protein thyroid hormone thyrotropin thyroxine angiogenesis animal experiment animal tissue article cancer growth cancer size cancer survival cell division controlled study female hyperthyroidism hypothyroidism immunoblotting in vivo study liothyronine blood level mouse nonhuman priority journal protein expression T cell lymphoma thyroxine blood level cell cycle thyroid hormones Animals Apoptosis Caspase 3 Cell Cycle Proteins Cell Line, Tumor Cell Proliferation Cyclin D1 Cyclin-Dependent Kinase Inhibitor p21 Cyclin-Dependent Kinase Inhibitor p27 Female Hyperthyroidism Hypothyroidism Lymphoma, T-Cell Mice Mice, Inbred C57BL Neoplasm Transplantation Neovascularization, Pathologic Proliferating Cell Nuclear Antigen Thyroid Gland Tumor Suppressor Protein p53
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00220795_v222_n2_p243_Sterle
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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