Obesity-programmed mice are rescued by early genetic intervention

Obesity is a chronic metabolic disorder affecting half a billion people worldwide. Major difficulties in managing obesity are the cessation of continued weight loss in patients after an initial period of responsiveness and rebound to pretreatment weight. It is conceivable that chronic weight gain un...

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Detalles Bibliográficos
Autores principales:	Bumaschny, V.F., Yamashita, M., Casas-Cordero, R., Otero-Corchón, V., De Souza, F.S.J., Rubinstein, M., Low, M.J.
Formato:	JOUR
Materias:	proopiomelanocortin tamoxifen animal cell animal experiment animal model article attenuation body weight comorbidity controlled study disease severity fatty liver female food intake gene expression gene targeting gene therapy hyperglycemia hyperinsulinemia hyperphagia hypothalamus locomotion male mouse nerve cell neurotransmission nonhuman obesity priority journal Adipose Tissue Adiposity Animals Disease Models, Animal Eating Hyperphagia Hypothalamus Mice Mice, Knockout Neurons Obesity Pro-Opiomelanocortin
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00219738_v122_n11_p4203_Bumaschny
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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