Delta aminolaevulinate dehydratase: its mechanism of action
1. 1. Taking into account available experimental data. a mechanism of action for aminolaevulinate dehydratase is proposed. 2. 2. Besides the formation of a Schiff base between the substrate and the enzyme, the existence of a minimal functional dimer necessary for activity is also considered, as well...
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| Autores principales: | , |
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_0020711X_v9_n12_p861_DelCBatlle |
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| Sumario: | 1. 1. Taking into account available experimental data. a mechanism of action for aminolaevulinate dehydratase is proposed. 2. 2. Besides the formation of a Schiff base between the substrate and the enzyme, the existence of a minimal functional dimer necessary for activity is also considered, as well as certain characteristics of the type of interactions involved in the inter-subunit contact sites and the role of histidine residues in the transport of protons from and to the active center. © 1978. |
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