Investigations on the presence of porphyrinogen carboxy-lyase inhibitor in the liver of rats intoxicated with hexachlorobenzene

1. 1. It has been reported that hexachlorobenzene (HCB) in vivo produces hepatic porphyrinogen carboxy-lyase (PCL) decrease and pentachlorophenol (PCP) is one of its metabolites. In order to investigate if such decrease is due to an enzyme inhibitor present in the porphyric livers, the effects of th...

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Detalles Bibliográficos
Autores principales:	De Molina, M.D.C.R., De Calmanovici, R.W., De Viale, L.C.S.M.
Formato:	JOUR
Materias:	2,4 dinitrophenol hexachlorobenzene pentachlorophenol animal experiment drug identification drug induced disease enzyme inhibition hepatic porphyria liver oral drug administration porphyrinogen carboxylase preliminary communication rat tetrachlorophenol Animal Benzene Biotransformation Carboxy-Lyases Chorionic Gonadotropin Coproporphyrinogens Female Hexachlorobenzene Liver Pentachlorophenol Porphyrinogens Rats Structure-Activity Relationship Support, Non-U.S. Gov't
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0020711X_v12_n5-6_p1027_DeMolina
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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