Trypanosoma cruzi: Antibodies to a MAP-like protein in chronic chagas' disease cross-react with mammalian cytoskeleton

Trypanosoma cruzi λgtll library from epimastogote derived mRNA was screened with human chagasic sera or sera from chronically infected mice. Strong reactive recombinants were detected with both sera. Two recombinant clones were studied in more detail and shown to be composed of the same 114-bp repet...

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Detalles Bibliográficos
Autores principales: Kerner, N., Liégeard, P., Levin, M.J., Hontebeyrie-Joskowicz, M.
Formato: JOUR
Materias:
cDNA library
Chagas' disease
Cytoskeleton
Immunoscreening
Molecular mimicry
Protozoa
Trypanosoma cruzi MAP-like antigen
autoantibody
hybrid protein
microtubule associated protein
microtubule associated protein 5
Microtubule Associated Proteins
microtubule-associated protein 1B
parasite antigen
protozoon antibody
amino acid sequence
animal
article
Chagas disease
chronic disease
cross reaction
cytoskeleton
immunology
molecular genetics
mouse
nucleotide repeat
nucleotide sequence
Amino Acid Sequence
Animal
Antibodies, Protozoan
Antigens, Protozoan
Autoantibodies
Base Sequence
Chagas Disease
Chronic Disease
Cross Reactions
Mice
Microtubule-Associated Proteins
Molecular Sequence Data
Recombinant Fusion Proteins
Repetitive Sequences, Nucleic Acid
Support, Non-U.S. Gov't
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00144894_v73_n4_p451_Kerner
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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