Augmented thromboxane generation by mesenteric arteries from pancreatectomized diabetic dogs is coincident with the vascular tone enhancement evoked by Na arachidonate and prostacyclin

We studied the relationships between acrachidonic acid (AA) metabolism and contractile responses to Na arachidonate (NaA) and the prostaglandins (PGs) in mesenteric arteries isolated from sham-operated and totally pancreatectomized dogs. PGE2 and PGF2α produced a similar dose-dependent relaxation of...

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Detalles Bibliográficos
Autores principales:	Sterin-Borda, L., Franchi, A.M., Borda, E.S., Castillo, E.D., Gimeno, M.F., Gimeno, A.L.
Formato:	JOUR
Materias:	6-oxo-PGF1α Arachidonic acid Arteries Cyclooxygenase Diabetes Insulin Lipoxygenase Mesenteric vessels Pancreatectomized dogs Prostacyclin Prostaglandins Thromboxane Vasoconstriction Vasodilation 5,8,11,14 icosatetraynoic acid acetylsalicylic acid arachidonic acid c 14 haloperidol imidazole indometacin insulin nordihydroguaiaretic acid phentolamine phentolamine mesylate prostacyclin prostaglandin synthase radioisotope thromboxane tranylcypromine unclassified drug animal model article diabetes mellitus dog drug efficacy endocrine system mesenteric artery nonhuman pancreas pancreas resection peripheral vascular system Animals Arachidonic Acid Arachidonic Acids Diabetes Mellitus, Experimental Dinoprost Dinoprostone Dogs Epoprostenol Mesenteric Arteries Muscle Tonus Muscle, Smooth, Vascular Pancreatectomy Prostaglandins E Prostaglandins F Thromboxanes
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00142999_v103_n3-4_p211_SterinBorda
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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