Injury elicited increase in spinal cord neurosteroid content analyzed by gas chromatography mass spectrometry

The effects of spinal cord injury (SCI), combined with castration and adrenalectomy, and of progesterone (PROG) treatment on neurosteroid levels and steroidogenic enzyme expression were investigated in the adult male rat spinal cord (SC). Steroid levels were quantified by gas chromatography/mass spe...

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Autores principales: Labombarda, F., Pianos, A., Liere, P., Eychenne, B., Gonzalez, S., Cambourg, A., De Nicola, A.F., Schumacher, M., Guennoun, R.
Formato: JOUR
Materias:
3(or 17)beta hydroxysteroid dehydrogenase
3alpha hydroxy 5alpha pregnan 20 one
5alpha pregnane 3,20 dione
cytochrome P450
messenger RNA
neurosteroid
pregnenolone
progesterone
steroid delta isomerase
adrenalectomy
animal experiment
article
biosynthesis
controlled study
gas chromatography
gonadectomy
male
mass spectrometry
nonhuman
priority journal
quantitative analysis
rat
reverse transcription polymerase chain reaction
spinal cord
17-Hydroxysteroid Dehydrogenases
5-alpha-Dihydroprogesterone
Animals
Cholesterol Side-Chain Cleavage Enzyme
Gas Chromatography-Mass Spectrometry
Male
Pregnanolone
Pregnenolone
Progesterone
Rats
Rats, Sprague-Dawley
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Spinal Cord
Spinal Cord Injuries
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00137227_v147_n4_p1847_Labombarda
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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