Increased pituitary vascular endothelial growth factor-A in dopaminergic D2 receptor knockout female mice

Vascular endothelial growth factor (VEGF)-A is an important angiogenic cytokine in cancer and pathological angiogenesis and has been related to the antiangiogenic activity of dopamine in endothelial cells. We investigated VEGF expression, localization, and function in pituitary hyperplasia of dopami...

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Autores principales:	Cristina, C., Díaz-Torga, G., Baldi, A., Góngora, A., Rubinstein, M., Low, M.J., Becú-Villalobos, D.
Formato:	JOUR
Materias:	3 (4,5 dimethylthiazol 2 yl) 5 (3 carboxymethoxyphenyl) 2 (4 sulfophenyl) 2h tetrazolium cell nucleus antigen dopamine 2 receptor dopamine 2 receptor blocking agent estrogen haloperidol messenger RNA prolactin tetrazolium thymidine tritium unclassified drug vasculotropin A dopamine receptor blocking agent drug derivative haloperidol decanoate angiogenesis animal cell animal experiment animal model animal tissue antigen expression article cell proliferation comparative study confocal laser microscopy controlled study correlation analysis female genotype hyperplasia hypophysis cell immunofluorescence test in vitro study in vivo study knockout mouse mouse nonhuman paracrine signaling priority journal prolactin release protein expression protein localization stellate cell umbilical vein wild type animal blood cell culture chemistry culture medium cytology drug effect genetics human hypophysis metabolism mouse mutant pathology tissue distribution Animals Cell Proliferation Cells, Cultured Culture Media, Conditioned Dopamine Antagonists Estrogens Female Haloperidol Humans Hyperplasia Mice Mice, Knockout Pituitary Gland Prolactin Receptors, Dopamine D2 RNA, Messenger Tissue Distribution Umbilical Veins Vascular Endothelial Growth Factor A
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00137227_v146_n7_p2952_Cristina
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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