Progesterone treatment reduces NADPH-diaphorase/nitric oxide synthase in Wobbler mouse motoneuron disease

Previous work demonstrated that progesterone (PROG) treatment attenuates morphological, molecular and functional abnormalities in the spinal cord of the Wobbler (Wr) mouse, a genetic model of motoneuron degeneration. Wr mice show a marked up-regulation of the nitric oxide synthesizing enzyme (NOS)....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	González Deniselle, M.C., Garay, L., López-Costa, J.J., González, S., Mougel, A., Guennoun, R., Schumacher, M., De Nicola, A.F.
Formato:	JOUR
Materias:	Endocrine and autonomic regulation Motoneuron disease Neuroendocrine regulation: other Neuroprotection Nitric oxide synthase Progesterone Wobbler mouse 3alpha hydroxy 5alpha pregnan 20 one 5alpha pregnane 3,20 dione methylprednisolone nitric oxide synthase progesterone reduced nicotinamide adenine dinucleotide phosphate dehydrogenase animal model animal tissue article astrocyte cell vacuole controlled study disease course drug blood level drug effect drug potency enzyme activity female histochemistry male motoneuron motor neuron disease mouse neuroprotection nonhuman phenotype priority journal white matter Animals Astrocytes Cell Count Down-Regulation Female Male Mice Mice, Neurologic Mutants Motor Neuron Disease Motor Neurons NADPH Dehydrogenase Nitric Oxide Synthase
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00068993_v1014_n1-2_p71_GonzalezDeniselle
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Progesterone treatment reduces NADPH-diaphorase/nitric oxide synthase in Wobbler mouse motoneuron disease
Publicado: (2004)

Progesterone receptors: A key for neuroprotection in experimental stroke
Publicado: (2012)

Progesterone receptors: A key for neuroprotection in experimental stroke
por: Liu, A., et al.

Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease
Publicado: (2005)

Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease
por: Gonzalez Deniselle, M.C., et al.

Progesterone effects on neuronal brain-derived neurotrophic factor and glial cells during progression of Wobbler mouse neurodegeneration
Publicado: (2012)

Progesterone effects on neuronal brain-derived neurotrophic factor and glial cells during progression of Wobbler mouse neurodegeneration
por: Meyer, M., et al.

Mice Brain nitric oxide synthase response induced by anaesthetics and other porphyrinogenic drugs
por: Lavandera, Jimena Verónica, et al.
Publicado: (2011)

Mice Brain nitric oxide synthase response induced by anaesthetics and other porphyrinogenic drugs
por: Lavandera, J., et al.

Steroid Effects on Glial Cells: Detrimental or Protective for Spinal Cord Function?
Publicado: (2003)

Steroid Effects on Glial Cells: Detrimental or Protective for Spinal Cord Function?
por: De Nicola, A.F., et al.

Decrease in salivary secretion by radiation mediated by nitric oxide and prostaglandins
por: Lomniczi, Alejandro, et al.
Publicado: (2006)

Decrease in salivary secretion by radiation mediated by nitric oxide and prostaglandins
por: De La Cal, C., et al.

Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration
Publicado: (2010)

Stage dependent effects of progesterone on motoneurons and glial cells of wobbler mouse spinal cord degeneration
por: Meyer, M., et al.

Effect of dexamethasone on nitric oxide (NO·) Production by cultured astrocytes
Publicado: (1999)

Effect of dexamethasone on nitric oxide (NO·) Production by cultured astrocytes
por: Llanos, S.L., et al.

Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease
Publicado: (2002)

Progesterone neuroprotection in the Wobbler mouse, a genetic model of spinal cord motor neuron disease
por: Gonzalez Deniselle, M.C., et al.

In vivo secretion of 3α-hydroxy-5α-pregnan-20-one, a potent anaesthetic steroid, by the adrenal gland of the rat
Publicado: (1985)

In vivo secretion of 3α-hydroxy-5α-pregnan-20-one, a potent anaesthetic steroid, by the adrenal gland of the rat
por: Holzbauer, M., et al.

Lack of nitric oxide-mediated regulation of amylase secretion stimulated by VIP in parotid glands of NOD mice
por: Roca, Valeria Inés, et al.
Publicado: (2004)

Lack of nitric oxide-mediated regulation of amylase secretion stimulated by VIP in parotid glands of NOD mice
por: Roca, V., et al.

Nitrogen depletion blocks growth stimulation driven by the expression of nitric oxide synthase in tobacco
por: Nejamkin, Andrés, et al.
Publicado: (2020)

Allopregnanolone (3α-Hydroxy-5α-pregnan-20-one) derivatives with a polar chain in position 16α: Synthesis and activity
por: Durán, Fernando Javier, et al.
Publicado: (2009)

Allopregnanolone (3α-Hydroxy-5α-pregnan-20-one) derivatives with a polar chain in position 16α: Synthesis and activity
por: Slavíková, B., et al.

Pleiotropic effects of 5-aminolevulinic acid in mouse brain
por: Lavandera, Jimena Verónica, et al.
Publicado: (2016)

Pleiotropic effects of 5-aminolevulinic acid in mouse brain
por: Lavandera, J., et al.

Effect of aminoguanidine, a nitric oxide synthase inhibitor, on ocular infection with herpes simplex virus in Balb/c mice
Publicado: (2001)

Effect of aminoguanidine, a nitric oxide synthase inhibitor, on ocular infection with herpes simplex virus in Balb/c mice
por: Benencia, F., et al.

Leptin enhances ovulation and attenuates the effects produced by food restriction
por: Ricci, Analía Gabriela, et al.
Publicado: (2005)

Leptin enhances ovulation and attenuates the effects produced by food restriction
por: Roman, E.A., et al.

Progesterone effects on neuronal ultrastructure and expression of microtubule-associated protein 2 (MAP2) in bats with acute spinal cord injury
Publicado: (2009)

Progesterone effects on neuronal ultrastructure and expression of microtubule-associated protein 2 (MAP2) in bats with acute spinal cord injury
por: González, S.L., et al.

Deoxycorticosterone stimulates the activity of nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase immunoreactivity in hypothalamic nuclei of rats
Publicado: (2002)

Deoxycorticosterone stimulates the activity of nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase immunoreactivity in hypothalamic nuclei of rats
por: Saravia, F.E., et al.

Defective signalling in salivary glands precedes the autoimmune response in the non-obese diabetic mouse model of sialadenitis
por: Rosignoli, Florencia, et al.
Publicado: (2005)

Defective signalling in salivary glands precedes the autoimmune response in the non-obese diabetic mouse model of sialadenitis
por: Rosignoli, F., et al.
Publicado: (2005)

Defective signalling in salivary glands precedes the autoimmune response in the non-obese diabetic mouse model of sialadenitis
por: Rosignoli, F., et al.
Publicado: (2005)

Defective signalling in salivary glands precedes the autoimmune response in the non-obese diabetic mouse model of sialadenitis
por: Rosignoli, F., et al.