Structural determinants of efficacy at A3 adenosine receptors: Modification of the ribose moiety
We have found previously that structural features of adenosine derivatives, particularly at the N6- and 2-positions of adenine, determine the intrinsic efficacy as A3 adenosine receptor (AR) agonists. Here, we have probed this phenomenon with respect to the ribose moiety using a series of ribose-mod...
Guardado en:
| Autores principales: | Gao, Z.-G., Jeong, L.S., Moon, H.R., Kim, H.O., Choi, W.J., Shin, D.H., Elhalem, E., Comin, M.J., Melman, N., Mamedova, L., Gross, A.S., Rodriguez, J.B., Jacobson, K.A. |
|---|---|
| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00062952_v67_n5_p893_Gao |
| Aporte de: |
Ejemplares similares
-
Structural determinants of efficacy at A3 adenosine receptors: Modification of the ribose moiety
por: Elhalem, Eleonora, et al.
Publicado: (2004) -
The role of the D2 dopamine receptor (D2R) in A2A adenosine receptor (A2AR)-mediated behavioral and cellular responses as revealed by A2A and D2 receptor knockout mice
por: Chen, J.-F., et al. -
The role of the D2 dopamine receptor (D2R) in A2A adenosine receptor (A2AR)-mediated behavioral and cellular responses as revealed by A2A and D2 receptor knockout mice
Publicado: (2001) -
Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model
por: Monczor, F., et al. -
Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model
por: Fernández, Natalia C., et al.
Publicado: (2003)