Studies on induction of δ-aminolevulinic acid synthase, ferrochelatase, cytochrome P-450 and cyclic AMP by phenformin. Chlorpropamide, allylisopropylacetamide and lead in hepatocytes from normal and experimental diabetic rats

The present work demonstrates that phenformin exerted an inducing effect on δ-amino-levulinic acid synthase (ALA-S) and ferrochelatase activities and on cytochrome P-450 content in isolated hepatocytes from rats with experimental diabetes. Similar results were obtained with respect to ALA-S activity...

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Detalles Bibliográficos
Autores principales:	Canepa, E.T., Llambias, E.B.C., Grinstein, M.
Formato:	JOUR
Materias:	5 aminolevulinate synthase allylisopropylacetamide bucladesine chlorpropamide cyclic amp cytochrome p450 ferrochelatase lead acetate phenformin phenobarbital animal cell animal experiment animal model article cell suspension drug concentration enzyme induction hepatic porphyria liver cell male nonhuman priority journal rat streptozocin diabetes 5-Aminolevulinate Synthetase Allylisopropylacetamide Animal Bucladesine Chlorpropamide Cyclic AMP Cytochrome P-450 Enzyme System Diabetes Mellitus, Experimental Enzyme Induction Ferrochelatase In Vitro Lead Liver Lyases Male Phenformin Rats Support, Non-U.S. Gov't
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00062952_v40_n2_p365_Canepa
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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